Grace of the Silent

♕ RPG roleplayer ♕
- worldbuilding-
consistency, constancy, control
Immersive and in-character roleplay


... • exploring brain regions beyond the visual cortex, such as the anterior cingulate cortex, which is commonly implicated in pain processing (Archibald et al., 2020;Gussew et al., 2010;Gutzeit et al., 2011;Mullins et al., 2005); • including a more diverse participant sample -beyond healthy controls -may help capture a wider range of H and E:I values, potentially improving sensitivity to metaboliterelated changes; • increasing sample size in order to detect small effect sizes; • using an event-related design, as opposed to the block design we used, may provide more sensitivity to detecting rapid and transient neural responses due to its ability to isolate specific events within the scan session (Mullins, 2018). However, see Pasanta et al. (2023) for a longer discussion and possible downsides to this approach; • and finally, using a combined fMRI-MRS sequence (Dwyer et al., 2021;Ip et al., 2017) to measure BOLD and Glu/GABA near-simultaneously. ...